Absorption properties of monolithic poly (divinylbenzene-co-N-vinylpyrrolidone) over a wide range of monomer ratios

The hydrophilic-lipophilic balance (HLB) polymers are able to directly extract polar and non-polar analytes from the aqueous samples, making them very popular for analytical separation SPE applications. However, commonly used suspension polymerization method preparing HLB is only efficiently prepare with low or medium mol percentages of hydrophilic monomer due partitioning into phase at higher concentrations. Thus, in this study a series based on divinylbenzene (DVB) (hydrophobic) N-vinylpyrrolidone (NVP) (hydrophilic) widely varying hydrophilicities were prepared by more robust monolith method. enabled preparation DVB-co-NVP polymer high NVP (0 mol% 55 NVP). comparative adsorption properties assessed using three polarity: adenosine (log P = ?1.5), caffeine ?0.07) p-toluidine 1.39). Interestingly, highest binding capacity was observed intermediate 30:70 feed ratio NVP/DVB, an optimal surface area hydrophilicity. Whereas, such as like adenosine, hydrophobic containing lower (20 NVP) superior.